Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

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成果类型：

期刊论文

作者：

Li, Wei;Yin, Shulu;Gong, Xiangyang;Xu, Wang;Yang, Ronghua;...

通讯作者：

Yuan, Lin(lyuan@hnu.edu.cn)

作者机构：

[Xu, Wang; Yuan, Lin; Li, Wei; Gong, Xiangyang; Yin, Shulu; Zhang, XiaoBing] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Peoples R China.

[Yang, Ronghua] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha, Peoples R China.

[Wan, Yichao] Hunan Univ Sci & Technol, Key Lab Theoret Organ Chem & Funct Mol MOE, Coll Chem & Chem Engn, Xiangtan 411201, Hunan, Peoples R China.

通讯机构：

[Lin Yuan] S

State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China

语种：

英文

期刊：

Chemical Communications

ISSN：

1359-7345

年：

2020

卷：

期：

页码：

1349-1352

DOI：

10.1039/c9cc08672b

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21735001, 21877029, 21622504]

机构署名：

本校为其他机构

院系归属：

化学与生物工程学院

摘要：

Herein, a novel two-photon ratiometric fluorescence assay was proposed for monitoring endogenous steroid sulfatase (STS) activity, which could be applied for the ratiometric imaging of STS activity in the endoplasmic reticulum of living cells and tissues and also could be used to distinguish estrogen-dependen...

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Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

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