The electronic properties of C2N/antimonene (Sb) van der Waals (vdW) heterostructure are investigated based on the density functional theory. The results show that the C2N/Sb vdW heterostructure behaves type-II band alignment with a direct Eg of 0.35 eV. The electronic structure can be adjusted by horizontal (vertical) strain, electric field, interlayer twist, and vertical strained-twisted cases, respectively. The horizontal strain shows a more extensive controlling range of Eg than the vertical strain, but the vertical strain adjusting shows better linear features than the horizontal strain. ...