Peptide aptamer-based colorimetric sensor for the detection of L-tryptophan in porcine serum

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成果类型：

期刊论文

作者：

Wang, Wenjing;He, Yumin;He, Suxiang;Liu, Xiaoying;Gui, Qing-wen;...

通讯作者：

Feng, ZM

作者机构：

[He, Yumin; Feng, Zemeng; Wang, Wenjing; He, Suxiang; Yin, Yulong] Chinese Acad Sci, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc,, Inst Subtrop Agr,Key Lab Agroecol Proc Subtrop Reg, Natl Engn Lab Pollut Control & Waste Utilizat Live, Changsha 410125, Peoples R China.

[He, Yumin] Univ South China, Hengyang Med Sch, Dept Biochem & Mol Biol, Hengyang 421001, Hunan, Peoples R China.

[Liu, Xiaoying; Gui, Qing-wen; He, Suxiang] Hunan Agr Univ, Coll Chem & Mat Sci, Changsha 410128, Hunan, Peoples R China.

[Deng, Lei] Cent South Univ, Sch Comp Sci & Engn, Changsha 410075, Hunan, Peoples R China.

[Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Trans, Changsha 410114, Hunan, Peoples R China.

通讯机构：

[Feng, ZM ] C

Chinese Acad Sci, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc,, Inst Subtrop Agr,Key Lab Agroecol Proc Subtrop Reg, Natl Engn Lab Pollut Control & Waste Utilizat Live, Changsha 410125, Peoples R China.

语种：

英文

关键词：

Peptide aptamer;Gold nanoparticle;L-tryptophan;Colorimetric sensor

期刊：

Microchemical Journal

ISSN：

0026-265X

年：

2024

卷：

197

页码：

109896

DOI：

10.1016/j.microc.2024.109896

机构署名：

本校为其他机构

院系归属：

化学与生物工程学院

摘要：

L-Tryptophan (L-Trp), one of the essential amino acids, is crucial for human physiological homeostasis and a limiting amino acid in animal feed. In addition, L-Trp is a precursor of some important biomolecules in the body, such as pentraxin and melatonin. Disorders of L-Trp metabolism in the body may cause Alzheimer's or Parkinson's disease. Therefore, monitoring L-Trp levels in the body fluids quickly and accurately is essential. A colorimetric biosensor was developed for the rapid detection of L-Trp in solutions by coupling a novel, screened, and validated peptide aptamer with Au nanoparticl...

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Peptide aptamer-based colorimetric sensor for the detection of L-tryptophan in porcine serum

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