期刊论文

Ning, Jingheng;Wang, Jianhui

英文

Molecules

1420-3049

2018

23

10

2688

10.3390/molecules23102688

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21505005, 31,527,803, 21545010]; National Key R&D Program of China [2017YFC1600306]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2018JJ2424]; Huxiang Youth talent Support Program [2015RS4051]

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Human epidermal growth factor receptor 2 (HER2) is a key tumor marker for several common and deadly cancers. It is of great importance to develop efficient detection methods for its over-expression. In this work, an electrochemical impedance spectroscopy (EIS) method adjustable by anionic porphyrin for HER2 gene detection has been proposed, based on the impedance difference between multi-walled carbon nanotubes (MWCNTs) and DNA. The interesting finding herein is that with the addition of anionic porphyrin, i.e., meso-Tetra(4-sulfophenyl)-porphy...