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A nanozyme-linked immunosorbent assay based on metal–organic frameworks (MOFs) for sensitive detection of aflatoxin B1

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成果类型:
期刊论文
作者:
Xu, Zhou*;Long, Ling-li;Chen, Yan-qiu;Chen, Mao-Long;Cheng, Yun-Hui*
通讯作者:
Xu, Zhou;Cheng, Yun-Hui
作者机构:
[Xu, Zhou; Chen, Yan-qiu; Long, Ling-li; Chen, Mao-Long; Cheng, Yun-Hui] Changsha Univ Sci & Technol, Coll Chem & Food Engn, Changsha 410114, Peoples R China.
通讯机构:
[Xu, Z; Cheng, YH] C
Changsha Univ Sci & Technol, Coll Chem & Food Engn, Changsha 410114, Peoples R China.
语种:
英文
关键词:
Aflatoxin B(1);MIL-88;MOFLISA;Nanozymes
期刊:
Food Chemistry
ISSN:
0308-8146
年:
2021
卷:
338
页码:
128039
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31401566, 31601550]; National Key R&D Program of China [2016YFF0203701]
机构署名:
本校为第一且通讯机构
摘要:
In order to avoid the occurrence of false positives and false negatives caused by conventional enzyme-linked immunosorbent assay (ELISA), we established a novel indirect competitive MOF-linked immunosorbent assay (MOFLISA) method for the high throughput and high sensitive detection of aflatoxin B1. This method replaces the natural enzyme with functional MOFs to catalyze a chromogenic system. As a result, the limit of detection (LOD) of the MOFLISA method was 0.009 ng·mL−1 with a linear working range from 0.01 to 20 ng·mL−1. The developed MO...

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