The effect of parameter combinations without using local search on improved ant colony algorithm is explored. Take vehicle routing problem with time windows (VRPTW) as an example, optimal configuration of five parameters in an improved ant colony algorithm based on max-min of ant colony algorithm is studied using uniform design. Simulation results show that the improved ant colony algorithm is valid for Solomon's R and RC data and has strong robustness. The reasons that local adjustment of the parameters does not significantly improve the...