期刊论文

L-Cystine Sensor Based on Modification of Extended Gate of FET with Polydithiodipropanesulfonic Acid Membrane

Xiao Zhongliang;Cao Zhong

中文

高等学校化学学报

0251-0790

2018

39

11

2386-2394

10.7503/cjcu20180283

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31527803, 21545010]

本校为第一且通讯机构

将场效应晶体管(FET)的栅极金电极(GGE)延长一定距离,在GGE表面自组装上聚二硫二丙烷磺酸(SPS)膜,构建了一种可检测L-胱氨酸(L-cystine)的新型传感装置.该传感界面的SEM表征、电化学性能测试和XPS分析结果表明,在溶液中带负电荷的SPS聚阴离子膜可通过静电作用吸附结合带正电荷的目标物L-胱氨酸,形成双电层结构而产生识别一价有机铵离子的膜电位.该电极在磷酸盐缓冲溶液(pH= 5.0)中对L-胱氨酸有良好的电位响应性能,线性范围为5.0 × 10~(-6) ~ 1.0 × 10~(-3) mol /L,响应灵敏度为(58.25 ± 1.5) mV/-pc(25 ℃) ,检出限为2.69×10~(-6) mol /L.该电极响应快(30 s) ,重现性及稳定性好.常见氨基酸如...

A novel sensing device capable of detecting L-cystine was constructed by designing the gate gold electrode(GGE) of a field effect transistor(FET) to extend a certain distance and self-assembly of polydithiodipropanesulfonic acid(SPS) on the surface of GGE. The topological structure of the modified GGE was characterized by means of scanning electron microscopy. Through electrochemical cyclic voltammetry and impedance analysis together with X-ray photoelectron spectroscopy, the response mechanism of the SPS modified GGE for the L-cystine detectio...