Based on the adsorption ability of a nano-sized iron metal-organic framework (Fe-MIL-88B-NH2) to a DNA aptamer, a fluorescent biosensor for BPA was developed. In this system, the aptamer was modified with a fluorescent dye as a fluorescent DNA probe. With the introduction of an Fe-MIL-88B-NH2 aqueous solution, the aptamer probe can be adsorbed by Fe-MIL-88B-NH2, and then the fluorescence of the dye will be quenched by Fe-MIL-88B-NH2. When the fluorescent DNA probes were mixed with a sample solution containing the target BPA, a recognition proce...