We investigate the asymptotic behavior of solutions to a nonlinear reaction-diffusion equation with distribution derivatives in the inhomogeneous term. Because the solutions of this equation are not very regular, i.e., u only belongs to Lp(Rn)∩H1(Rn), and ut is only in H-1(Rn) for the forcing term in H-1(Rn), the standard method does not directly work in our case. We demonstrate the asymptotic regularity of the solution to obtain the (L2(Rn),H1(Rn))-asymptotic compactness of the semigroup and therefore the existence of a (L2(Rn),H1(Rn))-global...