The prevalent oral diseases, such as dental caries, chronic gingivitis, and periodontitis, which are primarily caused by pathogenic bacteria, pose significant public health risks and impose substantial economic burdens. However, conventional treatment strategies for oral pathogens rely on mechanical debridement and antibiotic treatment, which remain unsatisfactory and contribute to the emergence of antimicrobial resistance pathogens. The escalating crisis of antibiotic resistance and the intricate microbial communities in oral niches urgently demand innovative antimicrobial strategies that can...