National Natural Science Foundation of China [20775010]; Hunan Provincial Natural Science Foundation of China [06JJ2038]; Hunan Provincial Education Department of China [05B020, 06C098]
机构署名:
本校为第一且通讯机构
院系归属:
化学与生物工程学院
摘要:
An optical biosensor with surface bound gold cap-shaped nano particles like polystyrene nanospheres has been constructed for detection of bio-molecules like antigen, antibody protein and DNA plasmid, which exhibited distinct optical properties of localized surface plasmon resonance (LSPR). It caused 1.09 nm red shift in the peak wavelength (lambdamax) of LSPR spectrum for the nanosensor exposed to c-Myc (3C7) mouse monoclonal IgG and 3.53 nm red shift to the corresponding antibody by the immuno -reaction subsequently. The kinetic process for the activity of the c-Myc (3C7) antigen lost with th...