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Preliminary investigation on an optical nanobiosensor based on Au cap-shaped polystyrene nanospheres

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成果类型:
期刊论文、会议论文
作者:
Cao, Zhong*;Huang, Xi-Xi;Yan, Feng;Gong, Fu-Chun;Li, He-Ping
通讯作者:
Cao, Zhong
作者机构:
[Li, He-Ping; Huang, Xi-Xi; Gong, Fu-Chun; Cao, Zhong] Changsha Univ Sci & Technol, Sch Chem & Environm Engn, 45 Chiling Rd, Changsha 410076, Hunan, Peoples R China.
[Yan, Feng] Hunan Normal Univ, Coll Life Sci, Changsha 410081, Hunan, Peoples R China.
通讯机构:
[Cao, Zhong] C
Changsha Univ Sci & Technol, Sch Chem & Environm Engn, 45 Chiling Rd, Changsha 410076, Hunan, Peoples R China.
语种:
英文
关键词:
nanobiosensor;Au cap-shaped nano particle;localized surface plasmon resonance;c-Myc
期刊:
2008 3RD IEEE INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS, VOLS 1-3
ISSN:
2474-3747
年:
2008
页码:
1156-1159
会议名称:
3rd IEEE International Conference of Nano/Micro Engineered and Molecular Systems
会议论文集名称:
International Conference on Nano-Micro Engineered and Molecular Systems NEMS
会议时间:
JAN 06-09, 2008
会议地点:
Sanya, PEOPLES R CHINA
会议主办单位:
[Cao, Zhong;Huang, Xi-Xi;Gong, Fu-Chun;Li, He-Ping] Changsha Univ Sci & Technol, Sch Chem & Environm Engn, 45 Chiling Rd, Changsha 410076, Hunan, Peoples R China.^[Yan, Feng] Hunan Normal Univ, Coll Life Sci, Changsha 410081, Hunan, Peoples R China.
会议赞助商:
IEEE, State Key Lab Multi Spectral Informat Proc Technol, Chinese Soc Micro Nano Technol, Ctr Micro & Nano Syst, IEEE Nanotechnol Council, Shenyang Inst Automat, Univ California, UCLA, Ctr Cell Control, Global Engn Technol Inst, Nanosurf AG, Smart Instruments Nanosci & Nanotechnol, US Army Int Technol Ctr, Pacific
出版地:
345 E 47TH ST, NEW YORK, NY 10017 USA
出版者:
IEEE
ISBN:
978-1-4244-1907-4
基金类别:
National Natural Science Foundation of China [20775010]; Hunan Provincial Natural Science Foundation of China [06JJ2038]; Hunan Provincial Education Department of China [05B020, 06C098]
机构署名:
本校为第一且通讯机构
院系归属:
化学与生物工程学院
摘要:
An optical biosensor with surface bound gold cap-shaped nano particles like polystyrene nanospheres has been constructed for detection of bio-molecules like antigen, antibody protein and DNA plasmid, which exhibited distinct optical properties of localized surface plasmon resonance (LSPR). It caused 1.09 nm red shift in the peak wavelength (lambdamax) of LSPR spectrum for the nanosensor exposed to c-Myc (3C7) mouse monoclonal IgG and 3.53 nm red shift to the corresponding antibody by the immuno -reaction subsequently. The kinetic process for the activity of the c-Myc (3C7) antigen lost with th...

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