期刊论文

Ruan Jianming

英文

武汉理工大学学报(材料科学版)(英文版)

1000-2413

2009

24

4

566-570

10.1007/s11595-009-4566-y

Funded by the National Natural Science Foundation of China（No.50774096）；

本校为其他机构

A micro-envioment for nerve cells and tissue growth were designed and constructed via surface modification of poly(L-lactide-co-glycolide)(PLGA) with chitosan and hydroxyapatite(HA). The poly(L-lactide-co-glycolide)/chitosan/hydroxyapatite (PLGA/chitosan/HA) conduits were manufactured by a combined solvent casting and particulate leaching technique. The conduits were highly porous with an interconnected pore structure and 76.5% porosity. Micropores with 50–100 micrometer diameter were formed in the conduits. In vivo application of PLGA/chitosa...

为神经细胞和织物生长的 micro-envioment 经由表面修正被设计并且构造 poly (L-lactide-co-glycolide )(PLGA ) 与 chitosan 和 hydroxyapatite (哈) 。(L-lactide-co-glycolide ) poly， /chitosan/hydroxyapatite (PLGA/chitosan/HA ) 水管被扔的联合溶剂和微粒沥滤技术生产。水管与互连的毛孔结构和 76.5% 孔是高度多孔的。有 50 100 测微计直径的 Micropores 在水管被形成。在为 10 公里的重建的 PLGA/chitosan/HA 水管的 vivo 申请，臀部的神经缺点被走的轨道分析估计，湿重量确定胫骨是前面的肌肉和组织学的评价。在在 vivo 的宿主老鼠的水管不能仅仅是一在支持神经再生有效但是能也导致...