Introduction of an interface layer on hydroxyapatite whisker/poly(L-lactide) composite and its contribution for improved bioactivity and mechanical properties

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成果类型：

期刊论文

作者：

Yi, Wen-Jun;Qiu, Zi-Shi;He, Hao;Liu, Bo;Wang, Mingyu;...

通讯作者：

Chao, Zi-Sheng;Li, Li-Jun;Shen, Yi

作者机构：

[He, Hao; Wang, Mingyu; Liu, Bo; Chao, Zi-Sheng; Yi, Wen-Jun; Qiu, Zi-Shi; Jiang, Min] Changsha Univ Sci & Technol, Coll Mat Sci & Engn, Changsha 410082, Hunan, Peoples R China.

[Li, Li-Jun] Hunan Inst Sci & Technol, Coll Chem & Chem Engn, Yueyang 414006, Peoples R China.

[Shen, Yan-Yu; Shen, Yi] Cent South Univ, Xiangya Hosp 2, Dept Orthopaed Dept, Changsha 410011, Hunan, Peoples R China.

通讯机构：

[Chao, Zi-Sheng; Shen, Yi] C

[Li, Li-Jun] H

Changsha Univ Sci & Technol, Coll Mat Sci & Engn, Changsha 410082, Hunan, Peoples R China.

Hunan Inst Sci & Technol, Coll Chem & Chem Engn, Yueyang 414006, Peoples R China.

Cent South Univ, Xiangya Hosp 2, Dept Orthopaed Dept, Changsha 410011, Hunan, Peoples R China.

语种：

英文

关键词：

Adhesion;Amines;Biocompatibility;Calcium compounds;Cell culture;Composite materials;Cyclodextrins;Ethylene;Flowcharting;Hydroxyapatite;Particle size;Stem cells;Surface roughness;Tensile strength;Dissolution precipitations;Hydroxyapatite whiskers;Medical device industry;Mesenchymal stem cell;Mineralized extracellular matrixes;Poly lactic acid;Structure preservation;Surface modification methods;Ethylenediaminetetraacetic acid

期刊：

Nanotechnology

ISSN：

0957-4484

年：

2020

卷：

期：

页码：

235703

DOI：

10.1088/1361-6528/ab767c

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21376068]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [Grant2017JJ2359]

机构署名：

本校为第一且通讯机构

院系归属：

材料科学与工程学院

摘要：

A hydroxyapatite whisker (w-HA) was synthesized via dissolution-precipitation by forming calcium-ethylene diamine tetra acetic acid (Ca-EDTA) complexing. The hydroxyapatite whisker was formed with precipitation of Ca2+ along the c-axis due to the space inhibition of Ca-EDTA complex during refluxing. The op-w-HA (oligomeric poly(lactic acid) modified w-HA), p-w-HA (poly(L-lactide) modified w-HA) and pc-w-HA (poly(L-lactide) and cyclodextrin modified w-HA) were obtained via the surface modification of w-HA. The particle size, surface charge and b...

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Introduction of an interface layer on hydroxyapatite whisker/poly(L-lactide) composite and its contribution for improved bioactivity and mechanical properties

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