期刊论文

中文

食品科学

1002-6630

2009

30

15

220-222

10.3321/j.issn:1002-6630.2009.15.052

湖南省自然科学基金项目（08JJ3024） 长沙市科技局科技计划项目（K069062-12）

本校为其他机构

目的:探讨局灶性脑缺血再灌注后应用白术多糖治疗对神经功能的保护作用.方法:采用局灶性脑缺血再灌注模型,28只雄性Sprague Dawley大鼠随机分为对照组、再灌注组、蒸馏水组及白术多糖组.再灌注24h进行神经功能缺损评分,取缺血区组织,分别检测其水分、Na~+、K~+含量,同时观察病理形态学改变情况.结果:白术多糖组神经功能缺损评分明显低于再灌注组及蒸馏水组(P

Objective： To study the neuroprotective effect of polysaccharide of Atractylodes macrocephala Koidz on focal cerebral ischemia reperfusion in rats. Methods： Rats were subjected to 1 h middle cerebral artery occlusion （MCAO） using an intraluminal nylon filament followed by 24 h reperfusion. Twenty-eight male Sprague Dawley rats were randomly divided into four groups： sham group, reperfusion group, distilled water group and polysaccharide ofAtractylodes macrocephala Koidz group. The neurological deficit score was determined and the contents ...