期刊论文

Synthesis and Fungicidal Activities of N-（3,5-Disubstituted-2-oxo-2,3--dihydrobenzo [d]oxazol-6-yl）- substituted Benzamide Compounds

中文

精细化工中间体

1009-9212

2008

38

5

15-18,39

10.19342/j.cnki.issn.1009-9212.2008.05.005

基金项目：国家自然科学基金资助项目（20872033）,湖南省自然科学基金资助项目（07JJ1003）.

本校为其他机构

为了寻找高效、广谱、低毒、低残留的环境友好性杀菌剂,采用活性亚结构拼接法,引入广谱生物活性的苯并噁唑酮基团,设计并合成了12个未见文献报道的N-(3,5-二取代基-2-氧-2,3-二氢苯并[d]噁唑-6-基)苯甲酰胺类化合物(3),所有目标化合物结构均通过1H NMR、IR、LC/MS确证.初步生物活性测试表明该类化合物具有较弱的杀菌活性.

In search of high-efficay, broad-spectrum, low-toxicity and environmentally-friendly fungicidal compounds to resolve the resistance problem of crop diseases to the commercial fungicides twelve novel N-（3,5-disuhstituted-2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl）- substituted benzamides （3） were designed and synthesized. Their structures were confirmed by IR, ′H NMR and LC/MS . Preliminary bioassay showed that these novel compounds had some fungi...