A topology optimization method of micro structures with multi-constraints is proposed based on feasible domain adjustments. A topological optimization model of micro structures is formed by treating the structural compliance as the objective function, and the volume, frequencies and displacements as constraint functions. Moreover, explicit approximate expressions of the objective function and constraint functions are constructed. Then, a feasible domain adjustment scheme and a dual algorithm are adopted. Several numerical examples are given to validate that the proposed method can be adopted t...