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Highly cysteine-selective fluorescent nanoprobes based on ultrabright and directly synthesized carbon quantum dots

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成果类型:
期刊论文
作者:
Chen, Xuejiao;Gong, Fuchun*;Cao, Zhong*;Zou, Wu;Gu, Tingting
通讯作者:
Gong, Fuchun;Cao, Zhong
作者机构:
[Gong, Fuchun; Gu, Tingting; Zou, Wu; Gong, FC; Cao, Zhong; Chen, Xuejiao] Changsha Univ Sci & Technol, Coll Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.
[Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
通讯机构:
[Gong, FC; Cao, Z; Cao, Zhong] C
Changsha Univ Sci & Technol, Coll Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.
Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
语种:
英文
关键词:
Carbon dots;Direct synthesis;Ultrabright;Cysteine-selective nanoprobes
期刊:
Analytical and Bioanalytical Chemistry
ISSN:
1618-2642
年:
2018
卷:
410
期:
12
页码:
2961-2970
基金类别:
Funding information This work was supported by the National Natural Science Foundation of China (Nos. 31527803 and 21545010).
机构署名:
本校为第一且通讯机构
院系归属:
化学与生物工程学院
摘要:
Strongly green fluorescent carbon dots (CQDs) have been directly synthesized from 2,4-diaminophenylhydrazine and 2-hydroxy-5-methylisophthalaldehyde through a facile solvothermal method. The novel CQDs exhibit high fluorescence quantum yield and excellent water solubility due to the abundant amino and hydroxy groups on their surface. The use of the as-prepared CQDs combined with Cu(2+) constructed a "turn-on" switch cysteine-responsive nanoprobe. In the CQDs-Cu(2+) assemblies, the binding of Cu(2+) to CQDs results in the fluorescence quenching of CQDs by electron transfer mechanism, while the ...

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