The influence of the noise impact on system parameters estimation was analyzed in this paper. Direct identification algorithm of modulation least square of continuous Hammerstein which without measurement noise interference was introduced and the estimation parameter of Hammerstein model was obtained by parameter separation method. According to least-square characteristic of noise, the unbiased estimate parameters of continuous Hammerstein model with measurement noise interference was gained through modulation of generalized least squares algorithm. The unbiased and high accuracy estimation of...