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SERS monitoring the dynamics of local pH in lysosome of living cells during photothermal therapy

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成果类型:
期刊论文
作者:
Luo, Rongxing;Li, Yinhui;Zhou, Qifeng;Zheng, Jing*;Ma, Dandan;...
通讯作者:
Zheng, Jing;Yang, Ronghua
作者机构:
[Luo, Rongxing; Tang, Pinting; Zheng, Jing; Yang, Ronghua; Zheng, J; Li, Yinhui; Ma, Dandan; Zhou, Qifeng] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
[Yang, Sheng; Yang, Ronghua; Qing, Zhihe] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China.
通讯机构:
[Zheng, J; Yang, RH] H
[Yang, Ronghua] C
Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China.
语种:
英文
期刊:
ANALYST
ISSN:
0003-2654
年:
2016
卷:
141
期:
11
页码:
3224-3227
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21405038, 21575018, 21305036]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities
机构署名:
本校为通讯机构
院系归属:
化学与生物工程学院
摘要:
In this communication, we propose a gold nanorod-based SERS nanotracker to monitor the local pH change during photothermal therapy (PTT). The dynamic SERS analysis indicated that the local pH of the lysosome in living cells increased during the PTT which would be helpful to understand the cellular metabolic processes and further facilitate the pho...

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