Dehydration of glycerol to acetol via catalytic reactive distillation was studied over copper chromite catalysts. The effects of reaction temperature, glycerol concentration, catalyst loading and glycerol-feed flow rate were studied. It was showed that temperature is key operation factor by which glycerol conversion and acetol selectivity are mainly determined. The optimum operation conditions were shown that reaction temperature 220-240°C, glycerol concentration 16.37-17.75mol/L...