Alcohols controlled selective radical cyclization of 1,6-dienes under mild conditions
作者：
Qin, Fu-Hua;Huang, Xun-Jie;Liu, Yi;Liang, Hongze;Li, Qiang;...
期刊：
中国化学快报：英文版 ,2020年31(12):3267-3270 ISSN：1001-8417
通讯作者：
Wei, Wen-Ting;He, Wei-Min
作者机构：
[Wei, Wen-Ting; Huang, Xun-Jie; Liang, Hongze; Liu, Yi; Qin, Fu-Hua] Ningbo Univ, Sch Mat Sci & Chem Engn, State Key Lab Base Novel Funct Mat & Preparat Sci, Ningbo 315211, Peoples R China.;[Li, Qiang] Liaocheng Univ, Sch Chem & Chem Engn, Inst Funct Organ Mol & Mat, Liaocheng 252059, Shandong, Peoples R China.;[He, Wei-Min; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.
通讯机构：
[Wei, Wen-Ting] N;[He, Wei-Min] C;Ningbo Univ, Sch Mat Sci & Chem Engn, State Key Lab Base Novel Funct Mat & Preparat Sci, Ningbo 315211, Peoples R China.;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.
关键词：
Green chemistry;Metal free;Cyclization;Alcohol;Pyrrolidinone
摘要：
An efficient procedure for the selective preparation of hydroxy-, carbonyl- and acetal-containing 2-pyrrolidinones has been developed through radical cyclization of 1,6-dienes initiated by alpha-C(sp(3))-H functionalization of alcohols. This protocol could be conducted at catalyst-free conditions at relatively low temperature (80 degrees C) by employing commercially available tert-butyl peroxybenzoate (TBPB) as the oxidant. (C) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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Ultrasound-assisted tandem synthesis of tri- and tetra-substituted pyrrole-2-carbonitriles from alkenes, TMSCN and N,N-disubstituted formamides
作者：
Gui, Qing-Wen;Teng, Fan;Ying, Sheng-Neng;Liu, Yang;Guo, Tao;...
期刊：
中国化学快报：英文版 ,2020年31(12):3241-3244 ISSN：1001-8417
通讯作者：
He, Wei-Min
作者机构：
[Teng, Fan; Gui, Qing-Wen; Liu, Yang; Ying, Sheng-Neng; Guo, Tao] Hunan Agr Univ, Coll Chem & Mat Sci, Changsha 410128, Peoples R China.;[Tang, Jian-Xin] Hunan Univ Technol, Sch Life Sci & Chem, Zhuzhou 412007, Peoples R China.;[He, Wei-Min; Chen, Jin-Yang; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.
通讯机构：
[He, Wei-Min] C;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.
关键词：
Green chemistry;Solvent-free;Tandem reaction;Dual role;Ultrasound
摘要：
An energy-saving and eco-friendly method for the efficient construction of various tri- and tetra-substituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes, TMSCN and N,N-disubstituted formamides within 40 min under metal-, solvent-free and mild conditions was developed. The dual role of iodine (catalyst and oxidant) notably simplified the reaction conditions and reduced the chemical waste generated (C) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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英文
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Copper(i)-catalyzed intermolecular cyanoarylation of alkenes: convenient access to α-alkylated arylacetonitriles
作者：
Chen, Xin-Jie;Gui, Qing-Wen;Yi, Rongnan;Yu, Xianyong* ;Wu, Zhi-Lin;...
期刊：
Organic & Biomolecular Chemistry ,2020年18(27):5234-5237 ISSN：1477-0520
通讯作者：
Yu, Xianyong;He, Wei-Min
作者机构：
[Yu, Xianyong; Chen, Xin-Jie] Hunan Univ Sci & Technol, Minist Educ, Sch Chem & Chem Engn, Key Lab Theoret Organ Chem & Funct Mol, Xiangtan 411201, Peoples R China.;[Yi, Rongnan] Hunan Univ, Dept Chem, Changsha 410082, Hunan, Peoples R China.;[Gui, Qing-Wen; He, Wei-Min; Huang, Ying; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Rans, Changsha 410114, Peoples R China.;[Wu, Zhi-Lin] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构：
[Yu, Xianyong] H;[He, Wei-Min] C;Hunan Univ Sci & Technol, Minist Educ, Sch Chem & Chem Engn, Key Lab Theoret Organ Chem & Funct Mol, Xiangtan 411201, Peoples R China.;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Rans, Changsha 410114, Peoples R China.
关键词：
Copper(I)-catalyzed;intermolecular cyanoarylation;α-alkylated arylacetonitriles
摘要：
A novel Cu(I)-catalyzed intermolecular cyanoarylation of alkenes with diaryliodonium salts as a radical arylating reagent and tetra-butylammonium cyanide as an electrophilic cyanating reagent was established. A broad range of α-alkylated arylacetonitriles were efficiently constructed in good to excellent yields under base- and oxidant-free and mild conditions.
语种：
英文
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LiTa2PO8 coated nickel-rich cathode material for improved electrochemical performance at high voltage
作者：
Xiao, Zhongliang;Chi, Zhenzhen;Song, Liubin* ;Cao, Zhong;Li, Anxian
期刊：
Ceramics International ,2020年46(6):8328-8333 ISSN：0272-8842
通讯作者：
Song, Liubin
作者机构：
[Chi, Zhenzhen; Li, Anxian; Xiao, Zhongliang; Song, Liubin; Cao, Zhong] Changsha Univ Sci & Technol, Sch Chem & Food Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410004, Hunan, Peoples R China.
通讯机构：
[Song, Liubin] C;Changsha Univ Sci & Technol, Sch Chem & Food Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410004, Hunan, Peoples R China.
关键词：
Lithium ion battery;High working voltage;High rate performance;Security;Cycling ability
摘要：
LiNi0.8Co0.1Mn0.1O2 (NCM) will have higher energy density at high voltage, but severe electrochemical polarization and capacity decay are likely to occur because of structural degradation. In this paper, LiTa2PO8 is used as a coating layer to modify the NCM. Covered with a 2–4 nm coating layer, the material structure does not change significantly, and the structure is more stable. More importantly, LiTa2PO8 has an ordered channel with three-dimensional Li+ ion transport, which plays a key role in improving Li+ transmission efficiency. The results show that the electrochemical properties of the material are significantly improved after coating at high voltage. After 100 cycles, the capacity retention increases from 71.58% to 84.85%, voltage stability also notably improved, the polarization is weaker, and the reversible charge and discharge capacity at high rate (3C) is significantly higher than that of raw materials. The change in morphology after 100 cycles proves that the LiTa2PO8 coating prevents direct contact between the cathode materials and the electrolyte, inhibits the side reaction and enhance the surface structure stability of the cathode materials. © 2019 Elsevier Ltd and Techna Group S.r.l.
语种：
英文
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Measuring Binding Constants of Cucurbituril-Based Host-Guest Interactions at the Single-Molecule Level with Nanopores
作者：
You, Yi;Zhou, Ke;Guo, Bingyuan;Liu, Quansheng;Cao, Zhong* ;...
期刊：
ACS SENSORS ,2019年4(3):774-779 ISSN：2379-3694
通讯作者：
Cao, Zhong;Wu, Hai-Chen
作者机构：
[You, Yi; Cao, Zhong] Changsha Univ Sci & Technol, Collaborat Innovat Ctr Micro Nano Biosensing & Fo, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.;[Zhou, Ke; Wu, Hai-Chen; Guo, Bingyuan] Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China.;[Liu, Quansheng; Liu, Lei] Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat & Nanosafety, Multidisciplinary Ctr, Beijing 100049, Peoples R China.
通讯机构：
[Cao, Zhong; Wu, Hai-Chen] C;Changsha Univ Sci & Technol, Collaborat Innovat Ctr Micro Nano Biosensing & Fo, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.;Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China.
关键词：
DNA probe;binding constant;cucurbituril;host-guest interactions;nanopore
摘要：
Cucurbiturils are one type of widely used macrocyclic host compound in supramolecular chemistry. Their peculiar properties have led to applications in a wide variety of research areas such as fluorescence spectroscopy, drug delivery, catalysis, and nanotechnology. However, the solubilities of cucurbiturils are rather poor in water and many organic solvents, which may cause accuracy problems when measuring binding constants with traditional methods. In this report, we aim to develop an approach to measure the binding constants of cucurbituril-based host-guest interactions at the single-molecule level. First, we covalently attach different guest compounds to the side-chain of DNA molecules. Then, excess cucurbiturils are incubated with DNA probes to form the host-guest complexes. Next, the modified DNA hybrids are threaded through α-hemolysin nanopore to generate highly characteristic current events. Finally, statistical analyses of the obtained events afford the binding constants of cucurbiturils with various molecules. This new approach provides a simple and straightforward method to compare binding strength of different host-guest complexes and may find applications for quantifying other macrocycle-based host-guest interactions. © 2019 American Chemical Society.
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英文
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Real-time surface plasmon resonance monitoring of site-specific phosphorylation of p53 protein and its interaction with MDM2 protein
作者：
Wu, Ling;He, Yuhan;Hu, Yuqing;Lu, Hanwen;Cao, Zhong;...
期刊：
ANALYST ,2019年144(20):6033-6040 ISSN：0003-2654
通讯作者：
Wang, Jianxiu
作者机构：
[Hu, Yuqing; Wu, Ling; Yi, Xinyao; Wang, Jianxiu; He, Yuhan; Lu, Hanwen] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;[Cao, Zhong] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.;[Wang, Jianxiu] Key Lab Hunan Prov Water Environm & Agr Prod Safe, Changsha 410083, Hunan, Peoples R China.
通讯机构：
[Wang, Jianxiu] C;[Wang, Jianxiu] K;Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;Key Lab Hunan Prov Water Environm & Agr Prod Safe, Changsha 410083, Hunan, Peoples R China.
摘要：
Phosphorylation serves as an important post-translational modification implicated in cellular signaling and regulation. In this work, real-time monitoring of site-specific phosphorylation of p53 protein by several protein kinases, followed by its interaction with MDM2 protein was conducted using surface plasmon resonance (SPR). The binding of phosphorylated p53 to MDM2 yields a smaller SPR signal in comparison with that in the case of unphosphorylated p53 protein. Three specific protein kinases were involved in the in situ phosphorylation of the surface-confined p53 protein, and the binding kinetics between the phosphorylated p53 and MDM2 protein was monitored. The results indicate that phosphorylation of Ser15 and Ser37 at the p53 transactivation domain 1 (TAD1) by DNA-dependent protein kinase (DNA-PK) is critical for inhibiting the p53-MDM2 interaction, and the weaker binding affinity is most likely caused by the hydrophobicity change in the vicinity of the MDM2-binding motif or phosphorylation-induced p53 conformational change. In contrast, phosphorylation of Ser46 at the p53 TAD2 domain by c-Jun NH2-terminal kinase 2 alpha 2 (JNK2 alpha 2) exerts a weaker influence on the binding affinity, whereas phosphorylation of Ser376 and Ser378 at the C-terminus of p53 by protein kinase C (PKC) appears to have little effect. The feasibility of the method for the screening of the DNA-PK inhibitor and the inhibitor of p53-MDM2 interaction has been demonstrated and the half-maximal inhibitory concentration (IC50) values of wortmannin and Nutlin-3 (21 nM and 83 nM, respectively) were highly comparable with those obtained by other methods. The proposed method holds great promise for monitoring protein phosphorylation and unraveling the post-translational modification mechanism.
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英文
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Visible-Light-Initiated Decarboxylative Alkylation of Quinoxalin-2(1 H)-ones with Phenyliodine(III) Dicarboxylates in Recyclable Ruthenium(II) Catalytic System
作者：
Xie, Long-Yong;Jiang, Li-Lin;Tan, Jia-Xi;Wang, Yi;Xu, Xiang-Qin;...
期刊：
ACS SUSTAINABLE CHEMISTRY & ENGINEERING ,2019年7(16):14153-14160 ISSN：2168-0485
通讯作者：
He, Wei-Min
作者机构：
[Wang, Yi; Jiang, Li-Lin; He, Wei-Min; Xu, Xiang-Qin; Tan, Jia-Xi; Xie, Long-Yong] Hunan Univ Sci & Engn, Dept Chem, Yangzi Tang Rd 130, Yongzhou 425100, Peoples R China.;[Zhang, Bo; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Wanjiali Rd 960, Changsha 410114, Hunan, Peoples R China.;[Tan, Jia-Xi] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Taoyuan Rd 1, Xiangtan 411201, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yangzi Tang Rd 130, Yongzhou 425100, Peoples R China.
关键词：
Alkylation;PEG 200;Quinoxalin-2(1 H)-ones;Recyclability;Visible-light catalysis
摘要：
A efficient and sustainable approach for the synthesis of 3-alkylquinoxalin-2(1H)-ones has been developed through visible-light-mediated decarboxylative alkylation of quinoxalin-2(1H)-ones with phenyliodine(III) dicarboxylates. This photocatalytic alkylation reaction could be conducted at ambient temperature by employing eco-friendly PEG-200 as the reaction medium. Various 3-alkylquinoxalin-2(1H)-ones were easily obtained through the present ruthenium(II) catalytic system, which could be successfully recycled five times without the significant decrease of its efficiency. Copyright © 2019 American Chemical Society.
语种：
英文
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A simple and effective strategy for detecting artemisinin based on oxidative cyclization of vitamin B1 eliciting fluorescence turn-on
作者：
Zou, Wu;Gong, Fuchun* ;Cao, Zhong* ;Xia, Jiaoyun;Gu, Tingting;...
期刊：
ANALYTICAL METHODS ,2019年11(1):88-96 ISSN：1759-9660
通讯作者：
Gong, Fuchun;Cao, Zhong
作者机构：
[Gong, Fuchun; Gu, Tingting; Zou, Wu; Gong, FC; Cao, Zhong; Deng, Renxing; Xia, Jiaoyun] Changsha Univ Sci & Technol, Coll Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.;[Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[Gong, FC; Cao, Z; Cao, Zhong] C;Changsha Univ Sci & Technol, Coll Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
摘要：
Artemisinin (ART) and its derivatives are first-line treatment drugs for falciparum malaria and save millions of lives every year. It is very difficult to design specific fluorescent probes for ART because ART has no groups for binding to except for the peroxide group. We find that alkaline-hydrolyzed ART (a-ART) can specifically recognize and react with vitamin B1 (VB1) and produce fluorimetrically detectable thiochromes. Notably, this chemistry is affected by very low concentrations of a-ART in a Tris-HCl buffer solution (pH 7.5) at room temperature, leading to >260-fold enhancement in the blue emission at 442 nm. By making use of the new signaling mechanism, an effective strategy for detecting ART was developed. The fluorescence intensity of the VB1-based probes linearly increased with increasing ART concentration ranging from 1 to 230 μM mL−1, and a detection limit as low as 11.5 nM mL−1 was achieved, making this method more sensitive than other reported UV-vis absorption and electrochemical methods. Moreover, this assay shows good selectivity over other ions and biomolecules. The proposed method was applied for the determination of ART in tablets and dried leaf samples of Artemisia annua L. with satisfactory results, which confirms its great potential for real sample analysis. The designed assay avoids the preparation of fluorescent probes, and all the detection processes are accomplished within 20 min. Therefore, VB1 can offer a simple, highly sensitive and selective sensing model for fluorescence detection of ART. © The Royal Society of Chemistry.
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英文
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Natural Deep Eutectic Solvent-Catalyzed Selenocyanation of Activated Alkynes via an Intermolecular H-Bonding Activation Process
作者：
Wu, Chao;Xiao, Hai-Jing;Wang, Shu-Wen;Tang, Man-Sheng;Tang, Zi-Long;...
期刊：
ACS SUSTAINABLE CHEMISTRY & ENGINEERING ,2019年7(2):2169-2175 ISSN：2168-0485
通讯作者：
He, Wei-Min
作者机构：
[Tang, Man-Sheng; Wu, Chao; Xiao, Hai-Jing; He, Wei-Min; Wang, Shu-Wen] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[Wu, Chao; Tang, Zi-Long; Xia, Wen] Hunan Univ Sci & Technol, Minist Educ, Key Lab Theoret Organ Chem & Funct Mol, Xiangtan 411201, Peoples R China.;[Li, Wen-Feng; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
关键词：
Deep eutectic solvent;Multicomponent reaction;Selenocyanation;Alkynes;H-bonding
摘要：
By employing cheap and biodegradable natural deep eutectic solvent as the catalyst and reaction media, the selective selenocyanation of activated alkynes via an intermolecular H-bonding activation pathway has been achieved, which allows for the efficient construction of various Z-vinyl selenolates. © 2019 American Chemical Society.
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英文
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Clean preparation of S-thiocarbamates with in situ generated hydroxide in 2-methyltetrahydrofuran
作者：
Bao, Wen-Hu;Wang, Zheng;Tang, Xiao;Zhang, Yun-Fu;Tan, Jia-Xi;...
期刊：
中国化学快报：英文版 ,2019年30(12):2259-2262 ISSN：1001-8417
通讯作者：
He, Wei-Min
作者机构：
[Zhang, Yun-Fu; Tang, Xiao; Bao, Wen-Hu; Wang, Zheng; He, Wei-Min; Tan, Jia-Xi] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[Cao, Zhong; Zhu, Qin] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.;[Tan, Jia-Xi] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China.;[Lin, Ying-Wu] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
关键词：
Green chemistry;Hydroxide;Biomass;S-Thiocarbamates;2-Methyltetrahydrofuran
摘要：
A simple and clean protocol for the synthesis of various alkyl and (hetero)aryl S-thiocarbamates was established. The usage of in situ generated hydroxide as both an oxygen source and hydrogen source as well as biomass-derived 2-methyltetrahydrofuran as a green reaction medium, the avoidance of phosphorus-containing reductant, and the generation of harmless water and nitrogen as the side-products have given the present method atom-economy and environmental friendliness. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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英文
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Effect of Zr doping and Li2O-2B(2)O(3) layer on the structural electrochemical properties of LiNi0.5Co0.2Mn0.3O2 cathode material: experiments and first-principle calculations
作者：
Song, Liubin;Li, Xinyu;Xiao, Zhongliang* ;Li, Lingjun;Cao, Zhong;...
期刊：
Ionics ,2019年25(5):2017-2026 ISSN：0947-7047
通讯作者：
Xiao, Zhongliang
作者机构：
[Xiao, Zhongliang; Song, Liubin; Li, Xinyu; Cao, Zhong] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410004, Hunan, Peoples R China.;[Zhu, Huali; Li, Lingjun] Changsha Univ Sci & Technol, Sch Mat Sci & Engn, Changsha 410004, Hunan, Peoples R China.
通讯机构：
[Xiao, Zhongliang] C;Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410004, Hunan, Peoples R China.
关键词：
LiNi0.5Co0.2Mn0.3O2;Co-modification;Electrochemical performance;Lithium-ion battery;First-principle calculations
摘要：
In order to enhance the electrochemical performance of LiNi0.5Co0.2Mn0.3O2 (NCM), an in situ doping with zirconium (Zr) by wet grind-solid state method then coating with Li2O-2B2O3 (LBO) by crystal phase selection method is successfully developed. At the same time, based on the density functional theory (DFT) with the generalized gradient approximation (GGA), use of the first-principle calculation method theoretically proved the experimental results. The XRD results of experimental and the calculated both revealed the lattice parameters become larger after Zr doped. The thickness of the LBO layer uniformly deposited on the surface of the Zr-doped sample is 5 nm, which can scavenge and neutralize HF erosion. Particularly, the Zr-doped and LBO-coated NCM sample exhibited excellent cycling performance with 90.5% capacity retention after 100 cycles at 1 C, which are apparently higher than 76.97% of NCM. The initial discharge capacity of double optimized sample was 170.4 mAh g−1 at 1 C which is higher than 157.1 mAh g−1 of NCM. Zr and LBO layers can effectively reduce the energy of the system and the band gap. Obtained results were consistent with the experimental results. Therefore, co-modification method plays an import role to optimize the material from the structure to the surface and hence greatly improved the battery performance. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.
语种：
英文
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Iodine-Catalyzed Odorless Synthesis of S-Thiocarbamates with Sulfonyl Chlorides as a Sulfur Source
作者：
Bao, Wen-Hu;He, Min;Wang, Jing-Ting;Peng, Xin;Sung, Men;...
期刊：
JOURNAL OF ORGANIC CHEMISTRY ,2019年84(10):6065-6071 ISSN：0022-3263
通讯作者：
He, Wei-Min
作者机构：
[He, Min; Bao, Wen-Hu; He, Wei-Min; Peng, Xin; Wang, Jing-Ting] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[Sung, Men; Tang, Zilong] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China.;[Jiang, Si; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
摘要：
A general and efficient protocol for the direct preparation of various S-thiocarbamates with readily available and inexpensive sulfonyl chlorides as an odorless sulfur source was developed. The employment of easily available reactants, excellent functional group tolerability, and mild reaction conditions make this process very practical.
语种：
英文
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DNA-templated copper nanoclusters obtained: Via TdT isothermal nucleic acid amplification for mercury(ii) assay
作者：
He, Jing-Lin;Wang, Xing-Xing;Mei, Ting-Ting;Wu, Ling;Zeng, Ju-Lan;...
期刊：
ANALYTICAL METHODS ,2019年11(32):4165-4172 ISSN：1759-9660
通讯作者：
Cao, Zhong
作者机构：
[Zeng, Ju-Lan; Wu, Ling; He, Jing-Lin; Wang, Xing-Xing; Wang, Jian-Hui; Mei, Ting-Ting; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Engn Res Ctr Food Proc Aquat Biot Reso, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.;[Wu, Ling; Wang, Jianxiu] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;[Yu, Donghong] Aalborg Univ, Dept Chem & Biosci, DK-9220 Aalborg, Denmark.;[Yu, Donghong] Sino Danish Ctr Educ & Res, DK-8000 Aarhus, Denmark.
通讯机构：
[Cao, Zhong] C;Changsha Univ Sci & Technol, Hunan Prov Engn Res Ctr Food Proc Aquat Biot Reso, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.
摘要：
Herein, DNA-templated copper nanoclusters (CuNCs) synthesized by terminal deoxynucleotidyl transferase (TdT) isothermal nucleic acid amplification (INAA) were proposed for Hg2+ assay. TdT recognized the 3′-OH end of primers and subsequently prolonged the single strand poly-T at 3′-OH with the assistance of deoxythymidine triphosphate (dTTP). The generated products coordinated with the copper ions to form DNA-templated CuNCs, resulting in remarkable fluorescence. The introduction of Hg2+ made the primers form a T-Hg2+-T mismatch duplex, which prevented the capture of the 3′-OH end by TdT. The poly-T single strand prolongation reaction was suspended; this led to fluorescence quenching. Hg2+ could be detected at a concentration as low as 76 pM with a significant linear range from 0.2 to 500 nM. This method, performed in one tube in one step, does not involve washing and separation steps, which provides a novel insight into the ultra-sensitive detection of toxic analytes in water quality applications. © 2019 The Royal Society of Chemistry.
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英文
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Hybridization chain reaction based DNAzyme fluorescent sensor for l-histidine assay
作者：
He, Jing-Lin* ;Zhang, Yang;Yang, Chan;Huang, Si-Ying;Wu, Ling;...
期刊：
ANALYTICAL METHODS ,2019年11(16):2204-2210 ISSN：1759-9660
通讯作者：
He, Jing-Lin;Cao, Zhong
作者机构：
[Zhang, Yang; He, Jing-Lin; Cao, Zhong; Yang, Chan; Mei, Ting-Ting; Huang, Si-Ying] Changsha Univ Sci & Technol, Sch Chem & Food Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.;[Wu, Ling; Wang, Jianxiu] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.
通讯机构：
[He, JL; Cao, Z] C;Changsha Univ Sci & Technol, Sch Chem & Food Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
摘要：
A hybridization chain reaction (HCR)-based DNAzyme fluorescent sensor is demonstrated for l-histidine (l-His) assays. l-His molecules initiate catalytic reactions to hydrolytic cleavage of the substrate strands of DNAzyme. The cleaved substrates open hairpin strands as primers, and thus trigger a cascade of hybridization events that yield a chain of G-quadruplex, which binds with porphyrin molecules to enhance its fluorescent intensity as a versatile signaling reporter. The linear range is from 5.0 × 10-9 mol L-1 to 5.0 × 10-6 mol L-1. The method reveals good recovery rates from 99.8% to 103% in real samples. In our work, the target enables the effective conversion of DNAzyme to active HCR. HCR amplified the oligonucleotide products, improving the signaling to the extent of the detection limit. Our work provides a rapid, accurate and enzyme-free means of target quantification. This approach is expected to extend the fabrication of target cleaving DNA biosensor systems for biological entities at room temperature. © The Royal Society of Chemistry.
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Metal-free C3-alkoxycarbonylation of quinoxalin-2(1H)-ones with carbazates as ecofriendly ester sources
作者：
Xie, Long-Yong;Peng, Sha;Fan, Tai-Gang;Liu, Yan-Fang;Sun, Meng;...
期刊：
中国科学：化学英文版 ,2019年62(4):460-464 ISSN：1674-7291
通讯作者：
He, Wei-Min
作者机构：
[Jiang, Li-Lin; Fan, Tai-Gang; He, Wei-Min; Liu, Yan-Fang; Xie, Long-Yong; Peng, Sha] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[Sun, Meng] Hunan Univ Sci & Technol, Minist Educ, Key Lab Theoret Organ Chem & Funct Mol, Xiangtan 411201, Peoples R China.;[Wang, Xing-Xing; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
关键词：
quinoxalin-2(1H)-ones;alkoxycarbonylation;carbazates;synthetic methods;metal-free
摘要：
Quinoxaline-3-carboxylates and analogues are prevalent key structural motifs in bioactive natural products and synthetic drugs. However, the practical protocol for preparation of these motifs from simple raw materials under mild conditions remains rare. In this article, we report a facile protocol for the efficient preparation of various quinoxaline-3-carbonyl compounds (30 examples, 63%–92%) through oxidation coupling of quinoxalin-2(1H)-ones with readily available carbazates (or acyl hydrazines) in the presence of K 2 S 2 O 8 as an oxidant in metal- and base-free conditions. When tert-butyl carbazate was used as the coupling reagent, the decarboxylation product 3-(tert-butyl)-1-methylquinoxalin-2(1H)-one was obtained. The application of this process into a gram-scale synthesis can be easily accomplished. Mechanistic investigations reveal that the functionalization of quinoxalin-2 (1H)-ones via a free-radical pathway. © 2019, Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature.
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Metal‐Free C3 Hydroxylation of Quinoxalin‐2(1H)‐ones in Water
作者：
Peng, Sha;Hu, Die;Hu, Jia-Li;Lin, Ying-Wu;Tang, Shan-Shan;...
期刊：
ADVANCED SYNTHESIS & CATALYSIS ,2019年361(24):5721-5726 ISSN：1615-4150
通讯作者：
He, Wei-Min
作者机构：
[He, Wei-Min; Tang, Hai-Shan; Tang, Shan-Shan; Hu, Die; Hu, Jia-Li; Peng, Sha] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[He, Wei-Min; He, Jun-Yi; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.;[Lin, Ying-Wu] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构：
[He, Wei-Min] H;[He, Wei-Min] C;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
关键词：
hydroxylation;quinoxalin-2(1H)-one;in water;TPGS-750-M;green chemistry
摘要：
A practical protocol for the preparation of quinoxaline-2,3(1H,4H)-diones through direct C(sp2)−H hydroxylation of quinoxalin-2(1H)-ones in recyclable DL-α-Tocopherol methoxypolyethylene glycol succinate solution (2 wt% in water) (TPGS-750-M/H2O) was developed. The target products were exclusively generated and could be collected through extraction and recrystallization. (Figure presented.). © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
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Clean Preparation of Quinolin-2-yl Substituted Ureas in Water
作者：
Xie, Long-Yong;Peng, Sha;Liu, Fang;Liu, Yan-Fang;Sun, Meng;...
期刊：
ACS SUSTAINABLE CHEMISTRY & ENGINEERING ,2019年7(7):7193-7199 ISSN：2168-0485
通讯作者：
He, Wei-Min
作者机构：
[He, Wei-Min; Liu, Yan-Fang; Xie, Long-Yong; Liu, Fang; Peng, Sha] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[Sun, Meng; Tang, Zi-Long] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China.;[Jiang, Si; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
关键词：
In water;Quinoline N-oxides;Atom economy;Reusability;Green chemistry
摘要：
An environmentally-friendly method for the clean preparation of various quinolin-2-yl substituted ureas in water under mild and toxic reagent-, base-, and organic solvent-free conditions was established. In the large-scale synthesis, the products could be rapidly collected via simple filtration and washing with ethanol. The usage of readily available raw materials, 100% atom economy, high yield, and excellent regioselectivity enhanced the practicability of this protocol. © 2019 American Chemical Society.
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Recent advances of 1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene (4CzIPN) in photocatalytic transformations
作者：
Shang, Tian-Yi;Lu, Ling-Hui;Cao, Zhong;Liu, Yan;He, Wei-Min* ;...
期刊：
Chemical Communications ,2019年55(38):5408-5419 ISSN：1359-7345
通讯作者：
He, Wei-Min;Yu, Bing
作者机构：
[Liu, Yan; Shang, Tian-Yi] Xinyang Agr & Forestry Univ, Coll Biol & Pharmaceut Engn, Xinyang 464000, Peoples R China.;[He, Wei-Min; Lu, Ling-Hui] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Wanjiali Rd 960, Changsha 410114, Hunan, Peoples R China.;[Liu, Yan] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Taoyuan Rd 9, Xiangtan 411201, Peoples R China.;[Yu, Bing] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China.
通讯机构：
[He, Wei-Min] H;[Yu, Bing] Z;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China.
摘要：
1,2,3,5-Tetrakis(carbazol-9-yl)-4,6-dicyanobenzene (4CzIPN) is a typical donor-acceptor fluorophore, with carbazolyl as an electron donor and dicyanobenzene as an electron acceptor. It has emerged as a powerful organophotocatalyst since 2016. Excellent redox window, good chemical stability and broad applicability make 4CzIPN an attractive metal-free photocatalyst. In this review, the recent advances of the application of 4CzIPN as a photoredox catalyst in the past three years (2016-2018) for various organic reactions are summarized.
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英文
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Solvent-dependent selective oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid under neat conditions
作者：
Liu, Kai-Jian;Zeng, Tang-Yu;Zeng, Jia-Le;Gong, Shao-Feng;He, Jun-Yi;...
期刊：
中国化学快报：英文版 ,2019年30(12):2304-2308 ISSN：1001-8417
通讯作者：
He, Wei-Min
作者机构：
[Zeng, Jia-Le; Zeng, Tang-Yu; Liu, Kai-Jian; He, Wei-Min; Gong, Shao-Feng] Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.;[He, Wei-Min; He, Jun-Yi; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Peoples R China.;[Tan, Jia-Xi] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China.;[Lin, Ying-Wu] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.
通讯机构：
[He, Wei-Min] H;Hunan Univ Sci & Engn, Dept Chem, Yongzhou 425100, Peoples R China.
关键词：
5-Hydroxymethylfurfural;2,5-Furandicarboxylic acid;Base-free;External initiator-free;Dioxygen
摘要：
An eco-friendly and economical route for the oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) with atmospheric dioxygen as the sole oxidant under acid-, base-, metal-, and external initiator-free conditions in minimal solvent was reported. In the present reaction, the 1,2-diethoxyethylane has a dual role: reaction medium and free-radical initiator. The FDCA easily crystallizes during the reaction and was simple purified via recrystallization to provide the pure FDCA. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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Electrochemical Studies and Molecular Dynamics Simulation of the Interaction between Accelerators and Cu Surface During the Electroplating Process
作者：
Xiao, Zhongliang;Zhou, Zhaohua;Song, Liubin;Wu, Daoxin* ;Zeng, Chao;...
期刊：
International Journal of Electrochemical Science ,2019年14(5):4705-4717 ISSN：1452-3981
通讯作者：
Wu, Daoxin
作者机构：
[Wu, Daoxin; Zhou, Zhaohua; Zeng, Chao; Xiao, Zhongliang; Song, Liubin; Cao, Zhong] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.
通讯机构：
[Wu, Daoxin] C;Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.
关键词：
Copper electroplating;Electrochemistry;MD simulation;SPS;ZPS
摘要：
Accelerators are crucial for electroplating in the electronics industry. In this research, the electrochemical behavior of two accelerators, 3-(benzothiazolyl-2-mercapto)-propyl-sulfonic acid sodium salt (ZPS) and bis(3-sulfopropyl) disulfide (SPS), during Cu electrodeposition was analyzed using electrochemical techniques. Meanwhile, the adsorption behavior of the two accelerators on Cu(111) was also studied using molecular dynamics (MD) simulation, which predicts the preferable reaction sites for nucleophilic or electrophilic attack and the corresponding interactions based on density functional theory. The MD results showed that ZPS could be adsorbed on the Cu(111) firmly through the thiouronium group and a benzothiazolyl group, whereas the SPS was adsorbed through the thiouronium group. Moreover, the accelerating efficiency of these two accelerators was closely related to the frontier molecule orbital density distributions and Fukui indices. © 2019 The Authors.
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