作者： Zhang, Li*;Su, Wei;Qian, Yihua;Chen, Tiansheng;Fan, Shengping;...

期刊： IEEJ Transactions on Electrical and Electronic Engineering,2019年14(11):1602-1608 ISSN：1931-4973

通讯作者： Zhang, Li

作者机构： [Zhang, Li; Su, Wei; Qian, Yihua; Chen, Tiansheng; Fan, Shengping; Fu, Qiang; Zhao, Yaohong] Guangdong Power Grid Co Ltd, Elect Power Res Inst, Guangzhou 510080, Guangdong, Peoples R China;[Zhu, Zhiping; Wang, Deng] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China

通讯机构： [Zhang, Li] G;Guangdong Power Grid Co Ltd, Elect Power Res Inst, Guangzhou 510080, Guangdong, Peoples R China.

关键词： transformer;defect;insulation resistance decline;aminopyrine;insulating oil

摘要： Recently, a kind of 110-kV transformer resistance decline defect was found during our routine preventive test of transformers in the Guangdong power grid. The number of defective transformers reached thirty. This phenomenon seriously threatened the safe and steady operation of the power grid. The analysis and treatment of this resistance decline defect were carried out. The key reason for this defect was confirmed. The insulating characteristics of insulating oil decreased. Aminopyrine is a kind of medicine used as an antipyretic analgesic. However, it was seldom investigated by the electric power industry. Aminopyrine as a potential contaminant was found to be present in insulating oils of transformers causing insulation resistance decline defect. Herein, the analysis process of defective insulating oils was introduced. The determination and quantitative detection of aminopyrine were performed using a gas chromatography-mass spectrometer, in which the highest concentration of aminopyrine in insulating oil was determined to be nearly 100 mg/kg. The source of aminopyrine was surveyed. Moreover, the impact mechanism between aminopyrine and insulating property of transformer oil was discussed. Finally, we found adsorption was effective for this defect. To date, this method has been applied to solve this defect in the Guangdong power grid. (c) 2019 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.

语种： 英文

作者： Song, Chunxia;Xu, Jingyuan;Chen, Ying;Zhang, Liangliang;Lu, Ying;...

期刊： Molecules,2019年24(22):4189- ISSN：1420-3049

通讯作者： Qing, Zhihe

作者机构： [Song, Chunxia; Lu, Ying; Zhang, Liangliang; Chen, Ying] Anhui Agr Univ, Sch Sci, Dept Appl Chem, Hefei 230036, Anhui, Peoples R China.;[Xu, Jingyuan; Qing, Zhihe] Changsha Univ Sci & Technol, Sch Chem & Food Engn, Hunan Prov Engn Res Ctr Food Proc Aquat Biot Reso, Changsha 410114, Hunan, Peoples R China.

通讯机构： [Qing, Zhihe] C;Changsha Univ Sci & Technol, Sch Chem & Food Engn, Hunan Prov Engn Res Ctr Food Proc Aquat Biot Reso, Changsha 410114, Hunan, Peoples R China.

关键词： DNA;ion;metal;nanomaterial;chemical structure;chemistry;DNA replication;fluorescence;genetic procedures;genetics;Biosensing Techniques;DNA;DNA Replication;Fluorescence;Ions;Metals;Molecular Structure;Nanostructures

摘要： DNA-templated fluorescent nanoclusters (NCs) have attracted increasing research interest on account of their prominent features, such as DNA sequence-dependent fluorescence, easy functionalization, wide availability, water solubility, and excellent biocompatibility. Coupling DNA templates with complementary DNA, aptamers, G-quadruplex, and so on has generated a large number of sensors. Additionally, the preparation and applications of DNA-templated fluorescent NCs in these sensing have been widely studied. This review firstly focuses on the properties of DNA-templated fluorescent NCs, and the synthesis of DNA-templated fluorescent NCs with different metals is then discussed. In the third part, we mainly introduce the applications of DNA-templated fluorescent NCs for sensing metal ions. At last, we further discuss the future perspectives of DNA-templated fluorescent NCs in the synthesis and sensing metal ions in the environmental and biological fields. © 2019 by the authors.

语种： 英文

作者： Jiang, Liu-Mo;Chen, Yu-Hang;Shu, Li;Zhang, Yu-Xiang;Xie, Ting;...

期刊： International Journal of Energy Research,2019年43(14):8385-8397 ISSN：0363-907X

通讯作者： Zeng, Ju-Lan

作者机构： [Xie, Ting; Wang, Shao-Fen; Zeng, Ju-Lan; Jiang, Liu-Mo; Shu, Li; Chen, Yu-Hang; Tan, Ni; Zhang, Yu-Xiang; Fang, Yu; Zhang, Ling] Changsha Univ Sci & Technol, Dept Chem, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.

通讯机构： [Zeng, Ju-Lan] C;Changsha Univ Sci & Technol, Dept Chem, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.

关键词： Aniline;Electric resistance measurement;Liquid sugar;Liquids;Nanowires;Polyaniline;Silver;Supercooling;Thermal conductivity;Crystallization rates;erythritol;Form stable phase change material;Low thermal conductivity;Polyanilines (PAni);Silver nanowires;Solid-liquid phase change materials;Surface polymerization;Phase change materials

摘要： Sugar alcohols are promising solid-liquid phase change materials (PCMs). However, problems such as possible leakage of liquid PCMs, high and unstable supercooling, and low thermal conductivity need to be solved. In this work, a novel form-stable PCM in which m-erythritol (ME), polyaniline (PANI), and silver nanowires (Ag NWs) were applied as solid-liquid PCM, supporting material, and thermal conductive filler, respectively, was successfully prepared in anhydrous ethanol by surface polymerization of aniline. Form-stable PCM with good form stability could be obtained when the ratio of ME/(aniline + ME) was no more than 78.7 wt%. The melting enthalpy (ΔHm) of the ME/PANI form-stable PCMs could attain 234.8 J/g while that of the ME/PANI/Ag NWs form-stable PCMs was about 220 J/g. In addition, the thermal conductivity of the form-stable PCM was increased by 61.6% when 7.5 wt% Ag NW was added. Moreover, the supercooling of ME was effectively suppressed from 100°C for pure ME to 60°C, corresponding to an improvement of 40%, for the form-stable PCM containing 7.5 wt% Ag NWs. The supercooling suppression could be ascribed to that PANI provided great amounts of nucleating centers and improved the nucleation kinetics, and Ag NWs improved the thermal diffusivity and thus increased the crystallization rate. © 2019 John Wiley & Sons, Ltd.

语种： 英文

作者： Zhang, Huibin;Gao, Haiyan;Liu, Xinli;Yu, Hang;Wang, Longfei;...

期刊： Separation and Purification Technology,2019年220:152-161 ISSN：1383-5866

通讯作者： He, Yuehui

作者机构： [Zheng, Guoqu; Wang, Longfei; Yu, Hang; Zhang, Huibin] Zhejiang Univ Technol, Coll Mat Sci & Engn, Hangzhou 310014, Zhejiang, Peoples R China.;[Gao, Haiyan; Liu, Xinli; Jiang, Yao; He, Yuehui; Zhang, Huibin] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China.;[Liu, Xinli] Cent S Univ, Coll Mat Sci & Engn, Changsha 410083, Hunan, Peoples R China.;[Gao, Lin] Intermet Technol Chengdu Co LTD, Chengdu 611731, Sichuan, Peoples R China.;[Yu, Linping] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.

通讯机构： [He, Yuehui] C;Cent S Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China.

关键词： Coal gas;FeAl;FeCrAl;Filtration;Intermetallic;Porous material

摘要： B2-structured Fe-20.5Al-18Cr (wt.%) intermetallic filter material developed for high-temperature coal-gas purification was fabricated by reactive synthesis using blended Fe/Al/Cr powders. This method addresses the problems presented in the manufacture of porous Fe-Al-Cr materials with high content of Al, making the production more convenient, flexible and controllable. The exothermic effect, volume swelling, pore formation and diffusion reactions during the reactive synthesis of porous Fe-20.5Al-18Cr were investigated systematically. A comparative study with porous Fe20Cr7Al material produced from prealloyed powders was carried out synchronously. The results show that during sintering the Fe-20.5Al-18Cr compact presents limited exothermic behavior and obvious volume expansion, and that the abundant pores and compositional homogenization can be obtained through the interactions of Fe/Al/Cr powders after final sintering. As compared with sintered Fe20Cr7Al porous material, porous Fe-20.5Al-18Cr possesses bigger permeability constants and lower oxidation and sulfidation rates. Pilot-scale filtration tests reveal that Fe-20.5Al-18Cr filter material can robustly serve in the corrosive H 2 S-contained and alkali-metals-oxides-loaded high-temperature coal gas during a period of 1000 h. © 2019 Elsevier B.V.

语种： 英文

作者： Wang, Deng;Zhu, Zhiping*;Zhang, Li;Qian, Yihua;Su, Wei;...

期刊： IEEE Transactions on Dielectrics and Electrical Insulation,2019年26(2):554-560 ISSN：1070-9878

通讯作者： Zhu, Zhiping

作者机构： [Zhu, Zhiping; Wang, Deng] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China.;[Chen, Tiansheng; Fan, Shengping; Zhao, Yaohong; Zhang, Li; Qian, Yihua; Su, Wei] Elect Power Res Inst Guangdong Power Grid Co Ltd, Guangzhou 410114, Guangdong, Peoples R China.

通讯机构： [Zhu, Zhiping] C;Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China.

关键词： degree of polymerization(DP);metal material;microstructure;oil-paper insulation;thermal aging

摘要： This study investigated the influence of the main metal materials of transformers on the oil-paper insulation performance. Ten types of insulating specimens were subjected to accelerated thermal aging at 120°C. Some aging parameters, including oil acid number, furfural content and degree of polymerization (DP) of insulating paper, were measured and compared. At the same time, we conducted frequency domain spectroscopy, X-ray diffraction, scanning electron microscopy and energy dispersive spectrometry on the insulating paper. The following conclusions were drawn: silicon lamination slightly deteriorates the insulating oil, copper increases the acidity and accelerates the production of furfural, metal materials can decrease DP of insulating paper and the effect of copper is greater than that of silicon lamination. During thermal aging, the dielectric dissipation factor of insulating paper increases and the carbon content of insulating paper increases. Metal materials can significantly increase the dielectric dissipation factor and carbon content of insulating paper and the effect of copper is greater than that of silicon lamination.

语种： 英文

作者： Zhang, Xue-Gang;Guan, Dan-Lin;Niu, Cheng-Gang*;Cao, Zhong;Liang, Chao;...

期刊： Science of The Total Environment,2019年668:730-742 ISSN：0048-9697

通讯作者： Niu, Cheng-Gang;Zeng, Guang-Ming

作者机构： [Guan, Dan-Lin; Zhang, Xue-Gang; Liang, Chao; Tang, Ning; Wen, Xiao-Ju; Zeng, Guang-Ming; Zhang, Lei; Niu, Cheng-Gang] Hunan Univ, Coll Environm Sci Engn, Key Lab Environm Biol Pollut Control, Minist Educ, Changsha 410082, Hunan, Peoples R China.;[Cao, Zhong] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.

通讯机构： [Niu, CG; Zeng, GM] H;Hunan Univ, Coll Environm Sci Engn, Key Lab Environm Biol Pollut Control, Minist Educ, Changsha 410082, Hunan, Peoples R China.

关键词： AgI/CuFe(2)O(4) photocatalyst;Antibacterial;Magnetic;Reusability and stability;Synergistic effect

摘要： Magnetic materials usually exhibit advanced performance in many areas for their easy separating and recycle ability. In this study, silver iodide/copper ferrite (AgI/CuFe2O4) catalysts with excellent magnetic property were successfully synthesized and characterized by a series of techniques. Two typical bacteria Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were applied to estimate the photocatalytic inactivation performance of obtained AgI/CuFe2O4 catalysts. Results revealed that the AgI/CuFe2O4 (12.5% AgI) composite could absolutely inactivate 3x10(9) CFU/mL E. coli and 2.7x10(8) CFU/mL S. aureus cells severally in 50min and 40min under visible light irradiation, which showed a much higher photo-disinfection activity than monomers. Transmission electron microscopy was used to study the biocidal action of this nanocatalyst, the results confirmed that the treated E. coli cells were damaged, the nanocatalyst permeated into cells and resulting in death of cells. Besides, it was found that the destruction of bacterial membrane together with substantial leaked potassium ion (K(+)) which caused by the photo-generated reactive species superoxide radical (O2(-)) and holes (h(+)) could be the direct disinfection principles. For a deep insight into practical applications, the influences of different catalyst concentrations and reaction pH were also taken into discussion in details. The overall results indicated the novel photocatalyst with strong redox capacity and outstanding reusability can be widely employed in bacteria elimination.

语种： 英文

作者： Zhang, Liwen;Guo, Qiuquan;Pitcheri, Rosaiah;Fu, Yi;Li, Jiangsheng;...

期刊： Journal of Power Sources,2019年413(Feb.15):233-240 ISSN：0378-7753

通讯作者： Qiu, Yejun

作者机构： [Pitcheri, Rosaiah; Fu, Yi; Zhang, Liwen; Qiu, Yejun] Harbin Inst Technol, Shenzhen Engn Lab Flexible Transparent Conduct Fi, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China.;[Guo, Qiuquan] Univ Western Ontario, Dept Mech & Mat Engn, London, ON N6A 5B9, Canada.;[Li, Jiangsheng] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.

通讯机构： [Qiu, Yejun] H;Harbin Inst Technol, Shenzhen Engn Lab Flexible Transparent Conduct Fi, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China.

关键词： Catalyst activity;Crystal structure;Crystals;Electrocatalysts;Electrolysis;Electrolytic reduction;Electroplating;Methanol;Microstructure;Morphology;Nanocatalysts;Nanofibers;Oxygen;Silver;Alternative catalysts;Electrocatalytic performance;Electrochemical measurements;Electroplating technique;Electrospinning process;Methanol tolerance;Structural sensitive;Synthesis parameters;Oxygen reduction reaction

摘要： Self-support silver nanofibers with excellent electrocatalytic performance for oxygen reduction reaction (ORR) are successfully fabricated through a hybrid method combining an electrospinning process with an electroplating technique. This nanofiber-based catalyst demonstrated superior long-term stability and an unusually high methanol-tolerant effect that its ORR activity was enhanced, instead of lessened in 3 M methanol. The impact of microstructure and crystal facet on ORR activity is examined through quantifying the performance of the catalysts by electrochemical measurements. Through tuning the synthesis parameters, the onset potential, half-wave potential, and peak potential of 1.041 V, 0.848 V, and 0.864 V are achieved for the silver nanofibers with thorny structure, even superior to those of commercial Pt/C catalyst. Such excellent performance is attributed to two major factors, the micro morphology, i.e. thorn-on-fiber structure, and the crystal facet. The special thorny structure leads to the accumulation of electrons on the tip to act as highly active sites and better confinement of the oxygen between thorns, while the high ratio of (110) facets on the tip favors high catalytic activity. This kind of low-cost silver nanofiber-based catalyst exhibits a highly beneficial prospect as a potential alternative catalyst for oxygen reduction reaction. © 2018 Elsevier B.V.

语种： 英文

作者： 杨佳;张煜杨;刘陈;李佳欣;肖忠良;...

期刊： 化学传感器,2018年38(02):1-11 ISSN：1008-2298

作者机构： 长沙理工大学化学与生物工程学院,电力与交通材料保护湖南省重点实验室,微纳生物传感与食品安全检测协同创新中心,湖南长沙 410114;[张煜杨; 杨佳; 肖忠良; 李佳欣; 刘陈; 曹忠; 李丹; 张玲] 长沙理工大学

关键词： 场效应晶体管;分析方法;化学/生物传感器;评述

摘要： 基于场效应晶体管的化学/生物传感器是近年来蓬勃发展的一种新型传感技术,具有输入阻抗高、噪声小、功耗低、动态范围大、易于集成、无二次击穿问题、安全工作区域宽等优点。该文介绍了场效应晶体管的基本结构、工作原理、性能参数以及分类,探讨了近几年场效应晶体管化学/生物传感器的研究与应用。

语种： 中文

作者： Xu, Zhou*;Zhang, Linwei;Mei, Bo;Tu, Jia;Wang, Rong;...

期刊： Coatings,2018年8(11):394- ISSN：2079-6412

通讯作者： Xu, Zhou;Cheng, Yunhui

作者机构： [Cheng, Yunhui; Xu, Zhou; Mei, Bo; Wang, Rong; Chen, Maolong; Zhang, Linwei; Cheng, YH] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.;[Tu, Jia] Hunan Acad Forestry, Changsha 410004, Hunan, Peoples R China.

通讯机构： [Xu, Z; Cheng, YH] C;Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.

关键词： Ag-coated Au nanoparticles;Detection;Pb2+;Surface-enhanced Raman scattering

摘要： A rapid surface-enhanced Raman scattering (SERS) method for Pb2+ detection has been developed based on l-cysteine-modified Ag-coated Au nanoparticles with core-shell nanostructure. Specifically, l-cysteine-functionalized Au@Ag core-shell probes bearing Raman-labeling molecules (4-ATP) are used to detect Pb2+ upon the formation of nanoparticle aggregates. The proposed SERS-based method shows a linear range between 5 pM and 10 nM, with an unprecedented limit of detection (LOD) of 1 pM for Pb2+; this LOD shows the method to be a few orders of magnitude more sensitive than the typical colorimetric approach that is based on the aggregation of noble metal nanoparticles. Real water samples diluted with pure water have been successfully analyzed. This SERS-based assay may provide a general and simple approach for the detection of other metal ions of interest, and so could have wide-ranging applications in many areas.

语种： 英文

作者： 杨盛;易梅;李丹;张玲

期刊： 广东化工,2018年45(18):190,198 ISSN：1007-1865

作者机构： 长沙理工大学化学与生物工程学院,湖南长沙,410114;长沙市长郡雨花外国语学校,湖南长沙,410114;[李丹; 张玲; 杨盛] 长沙理工大学;[易梅] 湖南省长沙市长郡雨花外国语学校

关键词： 生命化课堂;分析化学实验;课堂教学

摘要： 基于我院分析化学实验课程的特点和教学现状,本文以分析化学实验“试样中过氧化氢含量的测定”为例,探讨了构建具有生命力的分析化学实验课堂的四种策略:联系社会热点、注重教师语言魅力、巧设问题独立思考、成立互助合作小组.让学生成为课堂的主体尽情释放生命的活力.

语种： 中文

作者： 杨盛;易梅;李丹;张玲

期刊： 科教导刊：电子版,2018年(26):79,91 ISSN：1674-6813

作者机构： 长沙理工大学化学与生物工程学院 湖南·长沙 410114;长沙市长郡雨花外国语学校 湖南·长沙 410114;[李丹; 张玲; 杨盛] 长沙理工大学;[易梅] 湖南省长沙市长郡雨花外国语学校

关键词： 仪器分析;课程教学;生命化课堂

摘要： 针对仪器分析课程的特点及教学现状, 通过 “精选教学内容, 小组合作探究、 巧用多媒体” 三个方面, 使得课堂具有吸引力、 创造力和生命力. 让学生能够自主构建知识网络, 让知识的呈现能够多样化、 生命化, 从而呈现生命化的课堂.

语种： 中文

作者： Yang Jia;Zhang Yuyang;Liu Chen;Li Jiaxin;Xiao Zhongliang*;...

期刊： 高等学校化学学报,2018年39(11):2386-2394 ISSN：0251-0790

通讯作者： Xiao Zhongliang;Cao Zhong

作者机构： [Zhang Yuyang; Li Jiaxin; Zhang Ling; Cao Zhong; Yang Jia; Liu Chen; Xiao Zhongliang; Cao, Z; Li Dan] Changsha Univ Sci & Technol, Collaborat Innovat Ctr Micro Nano Biosensing & Fo, Sch Chem & Biol Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.

通讯机构： [Xiao, ZL; Cao, Z] C;Changsha Univ Sci & Technol, Collaborat Innovat Ctr Micro Nano Biosensing & Fo, Sch Chem & Biol Engn, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Changsha 410114, Hunan, Peoples R China.

关键词： L-胱氨酸;栅极金电极;场效应晶体管;聚二硫二丙烷磺酸;电位传感器

摘要： 将场效应晶体管(FET)的栅极金电极(GGE)延长一定距离,在GGE表面自组装上聚二硫二丙烷磺酸(SPS)膜,构建了一种可检测L-胱氨酸(L-cystine)的新型传感装置.该传感界面的SEM表征、电化学性能测试和XPS分析结果表明,在溶液中带负电荷的SPS聚阴离子膜可通过静电作用吸附结合带正电荷的目标物L-胱氨酸,形成双电层结构而产生识别一价有机铵离子的膜电位.该电极在磷酸盐缓冲溶液(pH= 5.0)中对L-胱氨酸有良好的电位响应性能,线性范围为5.0 × 10~(-6) ~ 1.0 × 10~(-3) mol /L,响应灵敏度为(58.25 ± 1.5) mV/-pc(25 ℃) ,检出限为2.69×10~(-6) mol /L.该电极响应快(30 s) ,重现性及稳定性好.常见氨基酸如L-甘氨酸、L-丙氨酸、L-缬氨酸、L-天冬氨酸、L-脯氨酸、L-苏氨酸、L-组氨酸、L-亮氨酸、L-色氨酸及L-甲硫氨酸等均不干扰电极对L-胱氨酸的测定.该电极可用于实际猪血清样品中L-胱氨酸的测定,回收率为91.2% ~ 107.8%,说明该方法是一种装置简便,能准确测定L-胱氨酸的新手段.

语种： 中文

作者： 李佑达;张玲;谭淑珍;王述维

期刊： 湖南文理学院学报(自然科学版),2017年29(1):19-23 ISSN：1672-6146

作者机构： 长沙理工大学化学与生物工程学院;[王述维] 长沙市如虹医药科技股份有限公司;[李佑达; 谭淑珍; 张玲] 长沙理工大学

关键词： 气相色谱法;顶空进样;埃索美拉唑钠;残留溶剂

摘要： 利用顶空气相色谱法测定了埃索美拉唑钠原料药中6种有机溶剂的含量。在该色谱条件下,6种有机溶剂均能彼此完全分离,峰面积与浓度呈现良好线性关系,相关系数均大于0.990。检出限（3S/N）分别为1.52、7.37、2.54、0.17、4.37、0.67μg/m L,定量限（10S/N）分别为2.83、10.92、7.93、0.34、9.83、2.69μg/m L。平均回收率均在98.74%108.59%范围内。该方法适用于实际样品的残留溶剂测定。

语种： 中文

作者： 曾巨澜;张雄飞;喻林萍;宋刘斌;张玲;...

期刊： 广东化工,2017年44(14):283-283 ISSN：1007-1865

作者机构： 长沙理工大学 化学与生物工程学院,湖南 长沙,410114;[曾巨澜; 张雄飞; 喻林萍; 宋刘斌; 张玲; 曹忠] 长沙理工大学 化学与生物工程学院

关键词： 虚拟仿真实验;物理化学实验;引导;监控

摘要： 本文探索了在物理化学虚拟仿真实验教学过程中,教师的引导与监控对学生进行实验的兴趣和积极性及教学效果的影响.教师对虚拟仿真实验进行适当的引导有助于取得积极的效果,但引导的程度是一个复杂的问题.同时教师应对虚拟仿真实验进行监控,以督促学生通过虚拟仿真实验取得积极的效果.

语种： 中文

作者： 曾巨澜;张玲;张跃飞;曹忠

期刊： 广东化工,2017年44(13):287-288 ISSN：1007-1865

作者机构： 长沙理工大学化学与生物工程学院,湖南长沙,410114;[曹忠; 张跃飞; 张玲; 曾巨澜] 长沙理工大学

关键词： 基础化学实验;示范实验室;实验技能;创新能力

摘要： 本文总结了长沙理工大学化学基础课示范实验室建设过程中所进行的探索和所获得的经验。突如了结合行业特色对基础化学实验进行分级教学与培训，以教师科研工作为平台开展创新研究性实验，增强了学生的实验技能和创新能力。

语种： 中文

作者： Jiang, Dawei;Sun, Yanhong*;Li, Jiang;Li, Qian;Lv, Min;...

期刊： ACS Applied Materials & Interfaces,2016年8(7):4378-4384 ISSN：1944-8244

通讯作者： Sun, Yanhong;Zhang, Lan;Wang, Lihua

作者机构： [Huang, Qing; Zhu, Bing; Sun, Yanhong; Zhang, Lan; Lv, Min; Li, Qian; Tian, Tian; Zhang, L; Wang, Lihua; Li, Jiang; Jiang, Dawei; Fan, Chunhai] Chinese Acad Sci, Div Phys Biol, Shanghai 201800, Peoples R China.;[Huang, Qing; Zhu, Bing; Sun, Yanhong; Zhang, Lan; Lv, Min; Li, Qian; Tian, Tian; Zhang, L; Wang, Lihua; Li, Jiang; Jiang, Dawei; Fan, Chunhai] Chinese Acad Sci, Shanghai Inst Appl Phys, CAS Key Lab Interfacial Phys & Technol, Bioimaging Ctr, Shanghai 201800, Peoples R China.;[Cheng, Dengfeng] Fudan Univ, Zhongshan Hosp, Dept Nucl Med, Shanghai 200032, Peoples R China.;[Xia, Jiaoyun] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China.;[Shi, Jiye] UCB Pharma, Slough SL1 14EN, Berks, England.

通讯机构： [Sun, YH; Zhang, L; Wang, LH] C;Chinese Acad Sci, Div Phys Biol, Shanghai 201800, Peoples R China.;Chinese Acad Sci, Shanghai Inst Appl Phys, CAS Key Lab Interfacial Phys & Technol, Bioimaging Ctr, Shanghai 201800, Peoples R China.

关键词： tetrahedral DNA nanostructures;tumor targeting;dual-modality imaging;single-photon emission computed tomography;near-infrared fluorescence

摘要： In this work, we have developed multiple-armed DNA tetrahedral nanostructures (TDNs) for dual-modality in vivo imaging using near-infrared (NIR) fluorescence and single-photon emission computed tomography (SPECT). We found that the presence of arm strands in TDNs remarkably enhanced their in vitro stability, allowing them to stay intact for at least 12 h in serum. By using NIR fluorescence imaging, we evaluated in mice the pharmacokinetics of TDNs, which exhibited distinctly different in vivo biodistribution patterns compared with those of double-stranded (ds)DNA. We also noticed that TDNs had twofold longer circulation time in the blood system than that of dsDNA. With the use of multiple-armed TDNs, we could precisely anchor an exact number of functional groups including tumor-targeting folic acid (FA), NIR emitter Dylight 755, and radioactive isotope 99mTc on prescribed positions of TDNs, which showed the capability of targeted imaging ability in cancer cells. Furthermore, we realized noninvasive tumor-targeting imaging in tumor-bearing mice by using both NIR and SPECT modalities. © 2016 American Chemical Society.

语种： 英文

作者： 张玲;冯雪;谭淑珍;王述维;李浦江

期刊： 长沙理工大学学报(自然科学版),2016年13(1):93-98 ISSN：1672-9331

作者机构： 长沙理工大学化学与生物工程学院;[王述维] 湖南如虹制药有限公司;[李浦江; 冯雪; 谭淑珍; 张玲] 长沙理工大学

关键词： 气相色谱法;顶空进样;雷贝拉唑钠;残留溶剂

摘要： 利用气相色谱法测定雷贝拉唑钠原料药中丙酮、乙腈、二氯甲烷、乙酸乙酯和甲苯5种有机溶剂残留量,通过优化实验条件建立了一种有效的测定有机溶剂残留量的方法。采用顶空毛细管气相色谱法,检测器为氢火焰离子化检测器,色谱柱为 DB-624石英毛细管柱,以氮气为载气,流速为2.0 mL/min；柱温采取程序升温方式,于40℃保持8 min,然后以每分钟20℃的速率升温至240℃,并保持20 min；顶空平衡温度为90℃,平衡时间为30 min；进样口温度为200℃,检测温度为250℃；进样体积为1 mL,分流比为5∶1。5种有机溶剂在该色谱条件下均能有效分离,峰面积与浓度呈现良好的线性关系,相关系数 R 圴大于0.990,检出限(3S/N)分别为0.616,6.72,4.89,2.70,1.46μg/mL,定量限(10S/N)分别为1.85,16.8,13.9,8.07,3.64μg/mL,各残留溶剂的加标回收率均在90%~110%范围内。

语种： 中文

作者： 何婧琳*;曹忠;李丹;张玲;谭淑珍;...

期刊： 大学化学,2016年31(8):27-32 ISSN：1000-8438

作者机构： 长沙理工大学化学与生物工程学院,长沙,410004;[何婧琳*; 李丹; 曹忠; 李伟; 谭淑珍; 陈平; 张玲] 长沙理工大学

关键词： 案例教学法;分析化学教学;案例分析

摘要： 研究了案例教学法在分析化学理论教学中的实践，内容包括案例选材、设计、实施和案例模型评估。案例教学法模式在促进学生扎实学习理论知识的同时，改进学生对于分析化学课程的认知，提高学生的专业技能。案例教学法在分析化学理论教学中的实践可以在教师教学和学生学习之间建立良好的互动关系，并最终改善分析化学课程教学。

语种： 中文

作者： Zhang, Li*;Su, Wei;Qian, Yihua;Zhao, Yaohong;Zhu, Zhiping;...

期刊： IEEE Transactions on Dielectrics and Electrical Insulation,2016年23(6):3429-3434 ISSN：1070-9878

通讯作者： Zhang, Li

作者机构： [Zhao, Yaohong; Zhang, Li; Qian, Yihua; Su, Wei] Guangdong Power Grid Co Ltd, Elect Power Res Inst, Guangzhou 510080, Guangdong, Peoples R China.;[Zhu, Zhiping; Wang, Deng] Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China.

通讯机构： [Zhang, Li] G;Guangdong Power Grid Co Ltd, Elect Power Res Inst, Guangzhou 510080, Guangdong, Peoples R China.

关键词： Di-n-butyl phthalate;impact evaluation;insulating oil.;Phthalate plasticizers;quantitative detection

摘要： Phthalate is one kind of widely applied plasticizers, which can improve the plasticity of various materials. Phthalate plasticizers are also added in food, in which the content is strictly controlled. However, they were seldom investigated by electric power industry. Recently, phthalate plasticizers were found to be present in many in-service insulating oils of transformers during our daily supervision work. Herein, the determination and quantitative detection of phthalate plasticizers in insulating oil was performed by gas chromatography-mass spectrometer (GC-MS). Di-n-butyl phthalate (DBP) was detected to be the major plasticizer in in-service oil samples, and the undesirable effect of DBP on the function of insulating oil was further evaluated. Finally, the sources of these phthalates in insulating oil were explored.

语种： 英文

作者： 吉丹丹;张玲;谭淑珍;薛琳

期刊： 理化检验-化学分册,2015年51(7):1010-1013 ISSN：1001-4020

作者机构： [吉丹丹; 张玲; 谭淑珍; 薛琳] 长沙理工大学化学与生物工程学院

关键词： 高效液相色谱法;右旋雷贝拉唑钠;对映体纯度

摘要： 采用高效液相色谱法测定右旋雷贝拉唑钠对映体的纯度.以α1-酸性糖蛋白键合硅胶为填充剂的CHIRALPAK-AGP手性柱为固定相,用乙腈-pH 6.0磷酸盐(1+9)混合溶液为流动相进行洗脱,用紫外检测器进行测定,检测波长为285 nm.左旋雷贝拉唑钠的质量浓度在38.4～576ug·L-1范围内与其峰面积呈线性关系,检出限(3S/N)为0.2 ng,测定下限(10S/N)为0.56 ng.加标回收率在91.1％～102％之间,测定值的相对标准偏差在2.4％～4.3％之间.

语种： 中文